Doc Green (the Hulk) visits attorney Matt Murdock (AKA Daredevil) at his San Francisco office. Doc is requesting documents provided by Bruce Banner. Murdock won't release them unless Doc turns into Banner. Doc does not want to comply and leaps away.
Later that night, Thunderbolt Ross approached Murdock on the streets. Ross found out about his reunion with the Hulk and wanted to know what it was about. Suddenly, Doc Green appears with the intention of depowering Ross. Visiting Murdock was a trick to locate Ross.
Ross turns into the Red Hulk and persuaded by Murdock, both powerhouses take their fight away from the city, to the Napa Valley. Doc takes the upper hand, and when he's about to stick his depowering syringe, Red destroys it, and breaks one of Doc's arms.
Doc opens a portal to his secret lab, the Beehive, to escape, but Red follows him. The fight resumes in the lab causing major destruction which compromises the lab's nuclear core. Doc's assistants, Damon Veteri and Randall Jessup, get the Gamma readings on Ross, and open a new portal through which Doc kicks Red through. Ross falls into an active volcano.
The Beehive is no longer safe. Doc, his assistants, and the A.I. (Project Omega) make it out using yet another portal. They arrive at the Baxter Building, the former headquarters of the Fantastic Four. The superhero team had been recently evicted from their building. Doc Green and his team should be safe and unnoticed there if they keep a low profile.
Meanwhile, Jennifer Walters, the original She-Hulk, gets a phone call from Murdock, alerting her of Doc's hunt for gamma spawn beings. The She-Hulk tells Murdock she'll handle it, as she grabs her Avengers membership card.